Accrington will launch the 2012/13 League Two campaign with a trip to Southend on August 18.
Stanley, who finished 14th last season, will play Port Vale in their first home game three days later (August 21) and welcome Exeter to the Crown Ground the following Saturday (August 25).
Accrington will travel to newly-promoted north-west rivals Fleetwood on November 20 and entertain them in the return on March 12 next year.
Paul Cook's side will play at Morecambe on November 6, with the home clash against the Shrimps coming on April 13 in their penultimate league fixture at the Crown Ground.
Accrington are scheduled to close the season with a home game against Oxford on April 27.