Chelsea took command of Champions League Group G thanks to a thumping 6-0 victory against Maribor at Stamford Bridge.
Luiz Adriano became the second player to score five in a Champions League match as Shakhtar thrashed BATE Borisov 7-0.
Bayern Munich struck five times in the first half en route to a 7-1 rout of Roma in Group E of the Champions League.
Lionel Messi drew level in the race to become the Champions League's all-time top goalscorer as Barcelona beat Ajax 3-1.
Eric Maxim Choupo-Moting scored a 92nd-minute penalty to earn Schalke a 4-3 win over Sporting Lisbon in Group G.