Southampton's on-loan duo Neal Trotman and Jacob Mellis will miss the Saints' FA Cup first-round trip to Bristol Rovers on Friday night.
Preston loanee Trotman and Chelsea youngster Mellis have been refused permission to play in the competition by their parent clubs.
Chris Perry or Wayne Thomas will step into the back four in place of Trotman, while Oscar Gobern could claim Mellis' spot on the bench.
Winger Michail Antonio has this week extended his loan spell from Reading, who have allowed him to play in the competition.
Saints are still without full-backs Graeme Murty (knee) and Lee Molyneux (back), although both are progressing well.
Striker Rickie Lambert, who scored 59 goals in three years with Rovers, returns to the Memorial Stadium for the first time since joining Saints in August.
The match kicks off at 7.45pm.


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