Shrewsbury's influential pair Shane Cansdell-Sherriff and Nicky Wroe have rejected new contracts in order to join Preston.
Shrews, who will compete in League One alongside North End next year following their automatic promotion, revealed last week they had offered the out-of-contract pair fresh terms to remain at the Greenhous Meadow.
But they have turned down the deals and will now officially join Preston on July 1 having both agreed two-year deals, with manager Graham Westley starting a rebuilding job at Deepdale having already snapped up Tranmere skipper John Welsh earlier this week.
Australian defender Cansdell-Sherriff, 29, joined Shrewsbury in 2008 and has made over 150 appearances for the club, including 43 this season.
Midfielder Wroe, 26, has also made 44 appearances this term in what was his first full season in Shropshire following his January 2011 move from Torquay.