West Ham defender James Collins will miss the visit of Manchester City on Saturday evening after suffering an injury on international duty.
The 30-year-old was replaced just before the hour in Wales' 1-1 draw with Belgium in midweek and Hammers boss Sam Allardyce confirmed he has a hamstring injury.
He joins Andy Carroll (heel) and Alou Diarra (knee) on the sidelines whilst Carlton Cole, who rejoined the club on a short-term deal last week, is not fit enough to be involved.
Defender Martin Demichelis is not yet ready to play, but is closing in on a first-team debut after pulling on a City shirt for the first time in the elite development squad's 2-2 draw with Rochdale on Wednesday.
The Argentinian defender joined City at the start of September from Atletico Madrid but damaged knee ligaments in his first week of training.
Captain Vincent Kompany (thigh) is definitely out, but like Demichelis he could be available next week. City's next fixtures are away to CSKA Moscow in the Champions League on Wednesday, and away to Chelsea on Sunday 27 October.
Midfielder Jack Rodwell also played in midweek and has declared himself fit and available for Saturday's game.