Marseille capitalised on Paris St Germain's defeat on Saturday to move level on points with Carlo Ancelotti's men at the top of Ligue 1 following a 2-0 victory at Ajaccio.
Andre Ayew opened the scoring nine minutes after the interval and his brother Jordan sealed victory in the closing stages to hand Ajaccio their first home defeat of the season.
PSG remain league leaders on goal difference but their shock home defeat to St Etienne on Saturday has put Marseille in the driving seat as it is they who have a game in hand.
Lyon moved within a point of the two frontrunners with a 5-2 triumph over Bastia in a madcap game at the Stade Gerland.
Maxime Gonalons and Alexandre Lacazette put Lyon in control but Wahbi Khazri and Jerome Rothen pulled Bastia level, the latter with a spot-kick after Dejan Lovren was sent off.
Lisandro Lopez restored Lyon's lead from 12 yards after Fethi Harek was dismissed and Jimmy Briand and Steed Malbranque scored in stoppage time, the latter from the spot, to give the scoreline a misleadingly one-sided look.
Toulouse failed to move level on points with PSG and Marseille after Yoan Gouffran's late strike gave Bordeaux a 1-0 win at Stade Chaban Delmas.
Le Tefece could have moved into second with victory in La Garonne derby but they were lacklustre throughout and Gouffran's close range strike three minutes from time sealed a deserved victory for Bordeaux.