Striker Fernando Torres will be back following his groin injury, but will start the match on the bench. Second-choice keeper Diego Cavalieri is also expected to play, with Jose Reina being rested.
Dirk Kuyt could sit out the match with boss Rafael Benitez confirming that several squad players will get a run-out. Reserve striker Daniel Pacheco is likely to be involved at some stage.
Liverpool (from): Cavalieri, Johnson, Carragher, Skrtel, Insua, Aquilani, Lucas, Mascherano, Gerrard, Riera, Ngog, Riera, Benayoun, Aurelio, Darby, Spearing, Kelly, Pacheco, Agger.