Bristol Rovers will be without the suspended Ben Swallow for the local derby.
Midfielder Swallow was sent off for a two-footed lunge late on in the Pirates’ 6-1 FA Cup second-round win at AFC Totton on Sunday and serves the first game of a three-match ban for the visit of the Robins.
Striker Eliot Richards is pushing for a start after coming off the bench to score twice in the same match, but the Welshman will have to oust Mustapha Carayol or Chris Zebroski.
Rovers are likely to be without veteran striker Scott McGleish (ankle), while experienced centre-back Adam Virgo has been ruled out for the season with knee ligament damage.
Midfielder Wayne Brown (ankle) could also be unavailable for the rest of the term.
Meanwhile, Swindon will be without key man Matt Ritchie on Saturday.
Winger Ritchie, who has been a prominent figure in the Robins’ recent 13-match unbeaten run in all competitions, picked up his fifth booking of the season at Southend in the Johnstone’s Paints Trophy southern section area semi-final on Tuesday and serves a one-match ban.
Lander Gabilondo and Etienne Esajas will both be looking to make the most of the ex-Portsmouth player’s suspension at the Memorial Stadium.
Striker Alan Connell will also be absent for Town. The former Grimsby frontman picked up an injury at Roots Hall in midweek and will not be fit enough to feature for manager Paolo Di Canio against Rovers.
Attacker Raffaele De Vita is expected to come back into the Swindon side after being rested in the JPT victory over the Shrimpers, while Simon Ferry is challenging for a starting berth in the middle of midfield.