Doherty missed last weekend’s game with Stockport after injuring the same ankle that he had problems with earlier in the season.
But the 30-year-old trained on Thursday and has not been ruled out of the game at Brunton Park on Saturday.
Matt Bloomfield and Stuart Beavon are both expected to be available despite struggling with illness.
However, Chairboys boss Waddock will be without on-loan QPR midfielder Gareth Ainsworth, who is struggling with a calf injury.
Leon Johnson (hip) remains a long-term absentee, along with Lewis Montrose, who is recovering from a cartilage operation on his knee.