Colchester goalkeeper Sam Walker is hoping to return to action in the home game against Scunthorpe.
Walker failed a late fitness test ahead of the midweek thrashing at Chesterfield due to a knee injury, but could replace Chris Lewington.
Skipper David Fox has missed the last four games due to a foot problem and remains doubtful, while striker Rhys Healey, defender Richard Brindley and midfielder Sammie Szmodics are pushing for recalls to the starting line-up.
The U’s, three points from safety, are looking to bounce back from Tuesday night’s 6-0 defeat at Chesterfield.
Scunthorpe’s teenage pair Kyle Wootton and Hakeeb Adelakun could be handed starts by boss Mark Robins.
Both players stepped off the bench to earn the Iron a point against Port Vale in midweek – striker Wootton headed home winger Adelakun’s cross – and Robins said they will be in contention.
Theo Robinson recently missed training due to the birth of his child and could be rested, while Neal Bishop will resume in midfield despite recently breaking his nose.
Defender Alex Davey is hoping to return after missing Tuesday night’s 1-1 draw against Port Vale due to a calf strain.
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