Everton captain Phil Jagielka will make a long-awaited return from injury in the FA Cup at home to Dagenham & Redbridge after more than two months out.
Full-back Seamus Coleman is sidelined for a month with a calf injury while in-form striker Romelu Lukaku and midfielder Tom Cleverley (calf) will not feature.
Midfielders Darron Gibson and Aiden McGeady are likely to be given some rare pitch time while South American summer signing Leandro Rodriguez is finally in line for his debut.
Midfielder Oliver Muldoon could make his Dagenham debut after signing on loan from Charlton for the rest of the season.
Josh Pask, Kyle Vassell, Ayo Obileye and James Dunne have returned to their parent clubs following the expiry of their loan deals.
Striker Zavon Hines (knee) and midfielder Matt Richards (Achilles) remain out.