Chelsea will host Manchester City for a place in the FA Cup quarter-finals, while Shrewsbury host Manchester United and holders Arsenal face Hull.
Chelsea and City will meet at Stamford Bridge in arguably the tie of the round next month, with both sides easing into the last 16 on the back of big away wins over the weekend; City seeing off Aston Villa 4-0 and MK Dons suffering a 5-1 home humbling to Chelsea.
Shrewsbury’s reward for seeing off Championship side Sheffield Wednesday is a home date with Louis van Gaal’s Manchester United, while holders Arsenal will face Hull – why they beat in the 2014 final – once again.
Leeds, in the last 16 for only the second time in 13 years, must travel to Watford, while they’ll be all Premier League ties at White Hart Lane, where Spurs will host Crystal Palace, and at Dean Court, where Bournemouth play Everton.
FA Cup fifth-round draw:
Chelsea v Manchester City
Reading v West Brom or Peterborough
Watford v Leeds United
Shrewsbury Town v Manchester United
Blackburn v Liverpool or West Ham
Tottenham v Crystal Palace
Arsenal v Hull
Bournemouth v Everton
Ties to be played on weekend 19-22 February.