Goals from Gianvito Plasmati, Chris Dagnall, Dean Cox and David Mooney also earned Mauro Milanese his first league win as O’s boss.
The home side went ahead with a classic centre-forward’s goal after 23 minutes. Italian striker Plasmati rose in the penalty area to meet a cross from Dagnall to send his header across Alex keeper Ben Garratt and into the net.
Strike partner Dagnall, a constant threat to the visitors, then doubled the lead 11 minutes later when he hammered a pass from Josh Wright low into the right-hand corner from 12 yards.
Orient started the second period in positive mode adding a third goal after 61 minutes when the tireless Dagnall raced onto a through pass by Romain Vincelot. Garratt was unable to hold the shot and Cox stabbed home the loose ball from close range.
The visitors pulled a goal back when Anthony Grant slammed home a 25-yard drive on 70 minutes to breathe spirit back into his side, but Orient ended their hopes after a move involving Cox and Dagnall teed up Mooney for the simplest of chances.
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