Former Cottagers defender Rosenior is working his way back to fitness following an ankle injury and is three or four weeks away.
Kayal is also recovering from an ankle problem which has sidelined him since September.
But boss Chris Hughton has no new injury concerns as the second-placed Seagulls attempt to extend their unbeaten run to 12 matches.
Fulham counterpart Slavisa Jokanovic again has a fully-fit squad to choose from.
Winger Floyd Ayite is over his recent ankle injury and came on as a substitute during the 1-1 draw with Sheffield Wednesday last weekend.
Jokanovic has named an unchanged side for the last three matches, in which Fulham have collected two wins prior to last Saturday’s stalemate.
Ayite, Ryan Sessegnon and Matt Smith are among the players pushing for recalls should Jokanovic opt to make changes.