Anthony Martial will against Sunderland bid to become the first player to score in his first three Premier League games for Manchester United.
Marcos Rojo misses out for Manchester United with a hamstring injury sustained against Southampton last weekend so Ashley Young could again fill in at left-back, as he did in the midweek Capital One Cup win over Ipswich, with Luke Shaw a long-term absentee.
United are also without Paddy McNair, and Louis van Gaal has already confirmed he will not move Daley Blind from his position in the centre of defence.
Jermain Defoe and Jack Rodwell are injury doubts for Sunderland with respective hamstring and ankle injuries, but Younes Kaboul is available again after serving his suspension in the midweek defeat at Manchester City.
- Manchester United have lost only one of their last 26 Premier League encounters with Sunderland (W1 D6 L19).
- Manchester United have conceded just two goals in their last five Premier League home games against Sunderland.
- Anthony Martial could become the first player to score in each of his first three Premier League appearances for Manchester United.
- Sunderland are looking for their 50th Premier League away win but have won just one of their last 14 on the road (D6 L7).
- The Black Cats are now on a nine-game winless streak in the Premier League (D4 L5); the longest current run in the competition.
- United have scored with all six shots on target in their last two Premier League games (versus Liverpool and Southampton).
- Sunderland have conceded 10 goals in the first half of PL games so far this season – of the other 19 teams, only Chelsea (12) have conceded more overall than this.
- After scoring in his first three consecutive matches against Man Utd in the PL, Jermain Defoe has only managed two goals in 18 PL apps versus them since.
- Antonio Valencia could make his 250th Premier League appearance in this game – the only other South American to reach this landmark is Nolberto Solano (302 PL apps).