The U’s have not played since the 2-1 win at Brighton on December 11 after last weekend’s home match with Carlisle was postponed.
Boothroyd has a full squad at his disposal apart from long-term absentees Scott Vernon, Lee Beevers and Ashley Vincent.
Vernon is back in light training after his recent knee injury but is some way from being fit, while Lee Beevers (shoulder) and winger Ashley Vincent (ankle) are still unavailable.
However, Colchester are boosted by the news that David Fox is back to full fitness.
Fox has played recent matches with a rib injury but the two-week break has allowed him to return to full fitness.