Southampton have agreed a fee of £11.5million with Celtic for Dutch defender Virgil van Dijk.
The 24-year-old will undergo a medical before signing a five-year deal at St Mary’s.
Van Dijk, who has been tracked by Southampton for the last 18 months, joined Celtic in 2013 after three years with Groningen and has won two successive league titles and the Scottish Cup with the Bhoys.
Meanwhile, Saints forward Emmanuel Mayuka, 24, has left to join Metz on a three-year deal.
The Zambia international, who was top scorer at the 2012 Africa Cup of Nations, joined Saints from Young Boys in the summer of 2012 and scored one goal in 19 appearances.
He spent the 2013-14 season on loan at French side Lorient and will return to France with Ligue 2 table toppers Metz.