Southampton will be without captain Jose Fonte and midfielder Sofiane Boufal when they face Liverpool in the first leg of the EFL Cup semi-final on Wednesday.
Manager Claude Puel does not intend to include Fonte, who put in a transfer request last week, until after the transfer window closes and Boufal has pulled out of playing in the African Nations Cup due to a knee injury.
Charlie Austin (shoulder), Matt Targett (hamstring), Cedric Soares (head) and Alex McCarthy (hamstring) all remain sidelined.
Liverpool playmaker Philippe Coutinho is set to make his return after nearly seven weeks out with ankle ligament damage but is likely to be on the bench.
Manager Jurgen Klopp is likely to recall most of his first-choice players having rested them for the weekend’s FA Cup tie but Loris Karius is set to continue in goal having had an inactive afternoon against Plymouth.
Captain Jordan Henderson (heel) will not resume full training until Thursday but centre-back Joel Matip (ankle) could make the squad as he seeks to prove his fitness ahead of Sunday’s trip to Manchester United.
Provisional Southampton squad: Forster, Van Dijk, Bertrand, Martina, Ward-Prowse, Hojbjerg, Romeu, Taylor, Yoshida, Davis, McQueen, Reed, Long, Sims, Redmond, Rodriguez, Tadic.
Provisional Liverpool squad: Karius, Alexander-Arnold, Lovren, Klavan, Milner, Can, Wijnaldum, Lallana, Coutinho, Ojo, Sturridge, Firmino, Mignolet, Clyne, Gomez, Moreno, Lucas, Stewart, Ejaria, Origi, Woodburn.