Kenya midfielder Wanyama will serve a one-match ban after picking up a 10th booking of the season in last weekend’s win against Hull – a match Djuricic missed with an ankle complaint which keeps him sidelined.
Ronald Koeman can call upon defender Florin Gardos again, although Fraser Forster, Jay Rodriguez and Emmanuel Mayuka remain absent.
Stoke will be without defender Marc Muniesa and winger Victor Moses.
Muniesa misses out due to a slight hamstring strain, while on-loan Moses has returned to parent club Chelsea because of a hamstring problem of his own that is expected to keep him sidelined for the rest of the season.
Defenders Marc Wilson and Erik Pieters are both nursing knocks to the wrist but manager Mark Hughes is hopeful the pair will be available for the visit of the Saints.