Vermaelen has been plagued by hamstring problems that he originally suffered while representing his country at last year’s World Cup before sealing his reported £14m move from Arsenal.
The 29-year-old had an operation on the injury in December, but could now have a role to play in Barca’s push for a treble of La Liga, Champions League and Copa del Rey.
“Five months after suffering an injury in his right hamstring, the Belgian player Thomas Vermaelen has been given the medical all-clear,” Barcelona said in a statement on Sunday.
Vermaelen’s return for Tuesday’s La Liga match at home to Getafe means coach Luis Enrique has a fully-fit squad to choose from for the first time this season.
Watch Barcelona v Getafe at 7pm on Sky Sports 5 on Tuesday.