Iain Hume opened the scoring for North End at St James Park on Saturday before Liam Sercombe equalised with a fine curling shot. But the visitors grabbed the points when Hume rounded Artur Krysiak to finish into an empty net after the Polish goalkeeper failed to collect Thorsten Stuckmann's long clearance.
"I am not despondent and I am not too disheartened by how we played," said Tisdale, whose side face a huge game against relegation rivals Wycombe on Tuesday.
"We had a lot of young players out there and it was a big step forward for the club and shows our trust in young players. It wasn't the worst afternoon we have had by any stretch of the imagination and I am not unhappy.
"I thought it was a great effort and we move on to Tuesday now. They are tough times, but what am I expecting of the performance when I am cobbling a team together and we aren't practising our routines and we don't know what the team will be from one minute to the next?
"All I can ask for is spirit and endeavour and try to free them up to show the odd bit of quality, which we did for the goal we scored. We have to keep putting the players out there and allow them to experience the fight. I have no real frustrations, especially with the younger players, who I thought were great."
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