Wright and van Aanholt are suspended, forcing Coleman to name two alternative full-backs.
Martin Cranie and Jordan Clarke look set to battle it out for the right-back spot to replace Wright.
On the left flank, Marcus Hall and Chris Hussey, who has yet to make his full debut for the club, are in contention to claim van Aanholt’s berth.
Winger Michael McIndoe has been struggling with flu-type symptoms this week and is a doubt for the Glanford Park clash.
Freddy Eastwood could be asked to deputise for McIndoe while midfielder Sammy Clingan remains a long-term absentee with a broken toe.