Derby County midfielder Duane Holmes is expected to be ruled out for several weeks after suffering an ankle injury against Huddersfield Town last weekend.
The USA international, who has made 25 appearances for the Rams this season, limped off in the first-half against the Terriers with a suspected ankle problem.
The 25-year-old, who began his playing career with Huddersfield Town, joined Derby in 2018 after excelling at Scunthorpe United and has become a key member of the squad ever since.
Defender Andre Wisdom was also forced off the pitch with a hamstring problem in the second half.
Speaking via Rams TV, Philip Cocu said: “That is a big blow because he has played some great football over a long period of time and is an important player for us.
“To lose a player like that at this stage isn’t something we can enjoy, but it gives someone else an opportunity to impress.”
Cocu’s side find themselves nine points adrift of the play-off places as they entertain automatic promotion hopefuls Fulham on Firday night at Pride Park.